diff --git a/AppImageBuilder.yml b/AppImageBuilder.yml
index ffd4159..86d0252 100644
--- a/AppImageBuilder.yml
+++ b/AppImageBuilder.yml
@@ -85,6 +85,8 @@ AppDir:
       # Path to the site-packages dir or other modules dirs
       # See https://docs.python.org/3/using/cmdline.html#envvar-PYTHONPATH
       PYTHONPATH: '${APPDIR}/usr/lib/python3.9/site-packages:${APPDIR}/usr'
+      # Force the AppImage to ignore local packages
+      PYTHONNOUSERSITE: 1
 
   test:
     fedora: